Tony L Yaksh Selected Research

Cyclooxygenase Inhibitors

1/2020	The neuropathic phenotype of the K/BxN transgenic mouse with spontaneous arthritis: pain, nerve sprouting and joint remodeling.
5/2010	Effects of intrathecal ketorolac on human experimental pain.
10/2004	Intrathecal protease-activated receptor stimulation produces thermal hyperalgesia through spinal cyclooxygenase activity.

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Tony L Yaksh Research Topics

Disease

61	Pain (Aches) 01/2022 - 01/2002
58	Hyperalgesia 01/2022 - 07/2001
23	Inflammation (Inflammations) 01/2019 - 01/2002
16	Neuralgia (Stump Neuralgia) 10/2021 - 07/2001
10	Hypersensitivity (Allergy) 01/2020 - 10/2002
9	Chronic Pain 01/2022 - 05/2010
8	Granuloma 01/2018 - 02/2003
4	Neoplasms (Cancer) 02/2017 - 05/2006
4	Postoperative Pain 01/2017 - 10/2008
3	Peripheral Nerve Injuries 01/2022 - 01/2002
3	Neuroinflammatory Diseases 01/2021 - 01/2018
3	Pruritus (Itching) 01/2020 - 04/2014
3	Polyneuropathies (Polyneuropathy) 07/2015 - 01/2013
3	Arthritis (Polyarthritis) 07/2012 - 11/2010
3	Sciatica (Sciatic Neuralgia) 04/2012 - 08/2004
3	Bone Neoplasms (Bone Cancer) 10/2008 - 10/2002
2	Peripheral Nervous System Diseases (PNS Diseases) 04/2022 - 01/2021
2	Intractable Pain 01/2021 - 02/2017
2	Infections 11/2020 - 07/2012
2	Wounds and Injuries (Trauma) 01/2020 - 01/2018
2	Erythema 01/2019 - 03/2002
2	Edema (Dropsy) 02/2017 - 01/2016
2	Demyelinating Diseases (Demyelinating Disease) 02/2017 - 05/2008
2	Migraine Disorders (Migraine) 07/2015 - 09/2014
2	Ganglion Cysts (Ganglion) 07/2015 - 09/2014
2	Paraparesis 11/2013 - 04/2003
2	Body Weight (Weight, Body) 01/2013 - 01/2002
2	Radiculopathy (Radiculopathy, Cervical) 04/2012 - 05/2009
2	Back Pain (Backache) 04/2012 - 05/2009
2	Burns 05/2010 - 01/2004
2	Osteosarcoma (Osteogenic Sarcoma) 10/2008 - 05/2006
2	Paraplegia (Spastic Paraplegia) 10/2007 - 11/2004
2	Ischemia 11/2004 - 04/2003

Drug/Important Bio-Agent (IBA)

19	Morphine (MS Contin)FDA LinkGeneric 12/2021 - 07/2001
18	Formaldehyde (Formol)FDA Link 12/2018 - 06/2003
17	CarrageenanIBA 10/2021 - 09/2003
12	Opioid Analgesics (Opioids)IBA 10/2021 - 04/2002
10	Proteins (Proteins, Gene)FDA Link 10/2021 - 03/2004
10	Analgesics (Analgesic Drugs)IBA 01/2021 - 07/2001
9	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 12/2018 - 10/2002
8	KetorolacIBA 01/2020 - 10/2002
8	Botulinum Toxins (Botulinum Toxin)IBA 01/2019 - 04/2014
7	Pharmaceutical PreparationsIBA 01/2022 - 09/2008
7	Gabapentin (Neurontin)FDA LinkGeneric 01/2020 - 09/2010
7	p38 Mitogen-Activated Protein KinasesIBA 03/2010 - 06/2003
6	Peptides (Polypeptides)IBA 01/2020 - 10/2004
6	N-Methylaspartate (NMDA)IBA 08/2016 - 06/2003
6	Substance PIBA 11/2013 - 09/2003
5	LipidsIBA 01/2021 - 08/2010
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2012 - 01/2002
4	Naloxone (Narcan)FDA LinkGeneric 12/2021 - 10/2002
4	Myelin Basic ProteinIBA 01/2020 - 08/2016
4	Opiate AlkaloidsIBA 10/2018 - 09/2006
4	Cisplatin (Platino)FDA LinkGeneric 01/2018 - 01/2013
4	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 10/2017 - 06/2003
4	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2014 - 10/2011
4	Opioid Receptors (Opioid Receptor)IBA 03/2013 - 12/2002
4	Etanercept (Enbrel)FDA Link 01/2013 - 04/2003
4	ProstaglandinsIBA 10/2004 - 10/2002
3	LipopolysaccharidesIBA 04/2022 - 12/2011
3	Cyclooxygenase InhibitorsIBA 01/2020 - 10/2004
3	Messenger RNA (mRNA)IBA 01/2019 - 04/2005
3	CytokinesIBA 01/2019 - 05/2009
3	Masoprocol (Actinex)FDA Link 12/2018 - 08/2010
3	GlucocorticoidsIBA 01/2017 - 05/2014
3	Methylprednisolone Acetate (Depo-Medrol)FDA LinkGeneric 01/2016 - 01/2012
3	Glutamic Acid (Glutamate)FDA Link 01/2016 - 01/2002
3	Neurotransmitter Agents (Neurotransmitter)IBA 12/2013 - 10/2002
3	substance P-saporinIBA 11/2013 - 05/2006
3	Neurokinin-1 Receptors (Neurokinin 1 Receptor)IBA 02/2011 - 01/2002
3	Dinoprostone (PGE2)FDA Link 05/2010 - 01/2004
3	Capsaicin (Zostrix)FDA Link 05/2010 - 01/2002
2	AutoantibodiesIBA 01/2022 - 01/2018
2	Bupivacaine (Bupivacaine Hydrochloride)FDA LinkGeneric 12/2021 - 05/2010
2	Sodium Channels (Sodium Channel)IBA 10/2021 - 01/2020
2	Sodium Channel BlockersIBA 01/2020 - 08/2016
2	Arachidonate 15-Lipoxygenase (Arachidonate 15 Lipoxygenase)IBA 12/2018 - 05/2013
2	Dizocilpine Maleate (Dizocilpine)IBA 10/2017 - 08/2016
2	AntigensIBA 02/2017 - 06/2016
2	LigandsIBA 08/2016 - 05/2013
2	Lidocaine (Xylocaine)FDA LinkGeneric 08/2016 - 07/2001
2	Calcium Channels (Calcium Channel)IBA 08/2016 - 01/2006
2	Interleukin-6 (Interleukin 6)IBA 08/2016 - 07/2012
2	Toll-Like Receptor 4IBA 01/2016 - 08/2010
2	InterferonsIBA 12/2013 - 05/2013
2	Alfentanil (Alfenta)FDA LinkGeneric 09/2013 - 01/2002
2	EnzymesIBA 05/2013 - 04/2012
2	Arachidonate 12-Lipoxygenase (12 Lipoxygenase)IBA 05/2013 - 08/2010
2	Ketamine FDA LinkGeneric 07/2010 - 01/2002
2	Protein Isoforms (Isoforms)IBA 03/2010 - 03/2005
2	Hydromorphone (Dilaudid)FDA LinkGeneric 03/2010 - 09/2006
2	Minocycline (Cyclops)FDA LinkGeneric 04/2009 - 11/2005
2	Phospholipases A2 (Phospholipase A2)IBA 04/2005 - 01/2002

Therapy/Procedure

11	Spinal Injections 04/2022 - 10/2002
11	Therapeutics 01/2022 - 03/2005
8	Ligation 10/2017 - 12/2002
6	Drug Therapy (Chemotherapy) 04/2022 - 10/2002
5	Catheters 01/2016 - 03/2002
3	Analgesia 10/2021 - 05/2010
2	Anesthesia 05/2010 - 04/2003